Gene: GNB4

Alternate names for this Gene: CMTD1F

Gene Summary: Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors.

Gene is located in Chromosome: 3

Location in Chromosome : 3q26.33

Description of this Gene: G protein subunit beta 4

Type of Gene: protein-coding

rs4855074 in GNB4 gene and Atrial Fibrillation PMID 29892015 2018 Multi-ethnic genome-wide association study for atrial fibrillation.

rs7611674 in GNB4 gene and Diastolic blood pressure PMID 30224653 2018 Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.