Gene: GNRH1

Alternate names for this Gene: GNRH|GRH|LHRH|LNRH

Gene Summary: This gene encodes a preproprotein that is proteolytically processed to generate a peptide that is a member of the gonadotropin-releasing hormone (GnRH) family of peptides. Alternative splicing results in multiple transcript variants, at least one of which is secreted and then cleaved to generate gonadoliberin-1 and GnRH-associated peptide 1. Gonadoliberin-1 stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Mutations in this gene are associated with hypogonadotropic hypogonadism.

Gene is located in Chromosome: 8

Location in Chromosome : 8p21.2

Description of this Gene: gonadotropin releasing hormone 1

Type of Gene: protein-coding