Gene: GOLGA3

Alternate names for this Gene: GCP170|MEA-2

Gene Summary: The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes a member of the golgin family of proteins which are localized to the Golgi. Its encoded protein has been postulated to play a role in nuclear transport and Golgi apparatus localization. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

Gene is located in Chromosome: 12

Location in Chromosome : 12q24.33

Description of this Gene: golgin A3

Type of Gene: protein-coding

rs11836108 in GOLGA3 gene and Body mass index PMID 30239722 2019 Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.

rs111696067 in GOLGA3 gene and Central Nervous System Neoplasms PMID 26424050 2015 Genome-wide association study identifies multiple susceptibility loci for glioma.

rs12282 in GOLGA3 gene and Cytokine Measurement PMID 22542470 2012 Genome-wide association study of antibody response to smallpox vaccine.

rs111696067 in GOLGA3 gene and Glioma PMID 26424050 2015 Genome-wide association study identifies multiple susceptibility loci for glioma.

rs2291256 in GOLGA3 gene and Smoking PMID 30643258 2019 Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.

rs74531549 in GOLGA3 gene and mathematical ability PMID 30038396 2018 Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.