Gene: GPC5

Alternate names for this Gene: -

Gene Summary: Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.

Gene is located in Chromosome: 13

Location in Chromosome : 13q31.3

Description of this Gene: glypican 5

Type of Gene: protein-coding

rs138994828 in GPC5 gene and Blood Protein Measurement PMID 31320639 2019 Genome and epigenome wide studies of neurological protein biomarkers in the Lothian Birth Cohort 1936.

PMID 29875488 2018 Genomic atlas of the human plasma proteome.

PMID 30072576 2018 Co-regulatory networks of human serum proteins link genetics to disease.

rs1411741 in GPC5 gene and Narcolepsy PMID 19629137 2009 Genome-wide association database developed in the Japanese Integrated Database Project.

rs16946160 in GPC5 gene and Nephrotic Syndrome PMID 21441931 2011 Common variation in GPC5 is associated with acquired nephrotic syndrome.

rs7328464 in GPC5 gene and Polysomnography PMID 23251661 2012 Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.

rs9516053 in GPC5 gene and Rheumatoid Arthritis PMID 30423114 2019 Genetic influences on susceptibility to rheumatoid arthritis in African-Americans.

rs7982677 in GPC5 gene and Tetralogy of Fallot PMID 23297363 2013 Genome-wide association study identifies loci on 12q24 and 13q32 associated with tetralogy of Fallot.

rs4771859 in GPC5 gene and response to antineoplastic agent PMID 23648065 2013 Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.