Gene: GPR39

Alternate names for this Gene: -

Gene Summary: This gene is a member of the ghrelin receptor family and encodes a rhodopsin-type G-protein-coupled receptor (GPCR). The encoded protein is involved in zinc-dependent signaling in epithelial tissue in intestines, prostate and salivary glands. The protein may also be involved in the pathophysiology of depression.

Gene is located in Chromosome: 2

Location in Chromosome : 2q21.2

Description of this Gene: G protein-coupled receptor 39

Type of Gene: protein-coding

rs3109133 in GPR39 gene and Calcium measurement PMID 25972035 2015 Association of common variants in the calcium-sensing receptor gene with serum calcium levels in East Asians.

rs10188442 in GPR39 gene and Hypertensive disease PMID 21626137 2011 Two-marker association tests yield new disease associations for coronary artery disease and hypertension.

rs12691825 in GPR39 gene and Leukemia, Myelocytic, Acute PMID 27903959 2017 Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.