Gene: GPR75-ASB3

Alternate names for this Gene: ASB-3|ASB3

Gene Summary: This locus represents naturally occurring read-through transcription between the neighboring GPR75 (G protein-coupled receptor 75) and ASB3 (ankyrin repeat and SOCS box containing 3) on chromosome 2. The transcript includes exons from both GPR75 and ASB3 and translation initiates in the 5' non-coding exon of GPR75. The resulting protein has a novel N-terminus but is otherwise identical to that encoded by ASB3.

Gene is located in Chromosome: 2

Location in Chromosome : 2p16.2

Description of this Gene: GPR75-ASB3 readthrough

Type of Gene: protein-coding

Gene: ASB3

Alternate names for this Gene: ASB-3

Gene Summary: The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Alternatively spliced transcript variants have been described for this gene.

Gene is located in Chromosome: 2

Location in Chromosome : 2p16.2

Description of this Gene: ankyrin repeat and SOCS box containing 3

Type of Gene: protein-coding

rs78694551 in GPR75-ASB3;ASB3 gene and Finding of Mean Corpuscular Hemoglobin PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs78694551 in GPR75-ASB3;ASB3 gene and RDW - Red blood cell distribution width result PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs78694551 in GPR75-ASB3;ASB3 gene and Red cell distribution width determination PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.