Gene: GPR85

Alternate names for this Gene: SREB|SREB2

Gene Summary: Members of the G protein-coupled receptor (GPCR) family, such as GPR85, have a similar structure characterized by 7 transmembrane domains. Activation of GPCRs by extracellular stimuli, such as neurotransmitters, hormones, or light, induces an intracellular signaling cascade mediated by heterotrimeric GTP-binding proteins, or G proteins (Matsumoto et al., 2000 [PubMed 10833454]).[supplied by OMIM, Aug 2008].

Gene is located in Chromosome: 7

Location in Chromosome : 7q31.1

Description of this Gene: G protein-coupled receptor 85

Type of Gene: protein-coding

rs2255811 in GPR85 gene and Triglycerides measurement PMID 25961943 2015 The impact of low-frequency and rare variants on lipid levels.