Gene: GPT
Alternate names for this Gene: AAT1|ALT1|GPT1
Gene Summary: This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.
Gene is located in Chromosome: 8
Location in Chromosome : 8q24.3
Description of this Gene: glutamic--pyruvic transaminase
Type of Gene: protein-coding
Gene: LOC101928953
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