Gene: GRIA3
Alternate names for this Gene: GLUR-C|GLUR-K3|GLUR3|GLURC|GluA3|MRX94|MRXSW
Gene Summary: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.
Gene is located in Chromosome: X
Location in Chromosome : Xq25
Description of this Gene: glutamate ionotropic receptor AMPA type subunit 3
Type of Gene: protein-coding