Gene: GRK2

Alternate names for this Gene: ADRBK1|BARK1|BETA-ARK1

Gene Summary: This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates including non-GPCR cell surface receptors, and cytoskeletal, mitochondrial, and transcription factor proteins. Data from rodent models supports a role for this gene in embryonic development, heart function and metabolism. Elevated expression of this gene has been observed in human patients with heart failure and Alzheimer's disease.

Gene is located in Chromosome: 11

Location in Chromosome : 11q13.2

Description of this Gene: G protein-coupled receptor kinase 2

Type of Gene: protein-coding