Gene: GRM5

Alternate names for this Gene: GPRC1E|MGLUR5|PPP1R86|mGlu5

Gene Summary: This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 11

Location in Chromosome : 11q14.2-q14.3

Description of this Gene: glutamate metabotropic receptor 5

Type of Gene: protein-coding

Gene: GRM5-AS1

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

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rs12273907 in GRM5;GRM5-AS1 gene and Narcolepsy PMID 19629137 2009 Genome-wide association database developed in the Japanese Integrated Database Project.