Gene: GTPBP1

Alternate names for this Gene: GP-1|GP1|HSPC018

Gene Summary: This gene is upregulated by interferon-gamma and encodes a protein that is a member of the AGP11/GTPBP1 family of GTP-binding proteins. A structurally similar protein has been found in mouse, where disruption of the gene for that protein had no observable phenotype.

Gene is located in Chromosome: 22

Location in Chromosome : 22q13.1

Description of this Gene: GTP binding protein 1

Type of Gene: protein-coding

rs4821816 in GTPBP1 gene and C-reactive protein measurement PMID 30388399 2018 Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.

rs138699 in GTPBP1 gene and Diverticular Diseases PMID 30177863 2018 Genome-wide association analyses identify 39 new susceptibility loci for diverticular disease.

rs2235229 in GTPBP1 gene and Duration of sleep PMID 30846698 2019 Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates.