Gene: GYPC

Alternate names for this Gene: CD236|CD236R|GE|GPC|GPD|GYPD|PAS-2|PAS-2'

Gene Summary: Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants.

Gene is located in Chromosome: 2

Location in Chromosome : 2q14.3

Description of this Gene: glycophorin C (Gerbich blood group)

Type of Gene: protein-coding