Gene: H2BU1

Alternate names for this Gene: H2Bb|HIST3H2BB

Gene Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene contain a palindromic termination element.

Gene is located in Chromosome: 1

Location in Chromosome : 1q42.13

Description of this Gene: H2B.U histone 1

Type of Gene: protein-coding

rs2147959 in H2BU1 gene and Asthma PMID 27611488 2017 Identification of Four Novel Loci in Asthma in European American and African American Populations.