Gene: HACD2

Alternate names for this Gene: PTPLB

Gene Summary: The protein encoded by this gene can catalyze the third step (dehydration) in the conversion of long chain fatty acids to very long chain fatty acids. The encoded protein localizes to the endoplasmic reticulum membrane.

Gene is located in Chromosome: 3

Location in Chromosome : 3q21.1

Description of this Gene: 3-hydroxyacyl-CoA dehydratase 2

Type of Gene: protein-coding

rs10668 in HACD2 gene and Body mass index PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

PMID 30239722 2019 Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.

rs16834426 in HACD2 gene and Duration of sleep PMID 30804565 2019 Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways.