Gene: HECTD3

Alternate names for this Gene: -

Gene Summary: The protein encoded by this gene transfers ubiquitin from an E2 ubiquitin-conjugating enzyme to targeted substrates, leading to the degradation of those substrates. The encoded protein has been shown to transfer ubiquitin to TRIOBP to facilitate cell cycle progression, and to STX8.

Gene is located in Chromosome: 1

Location in Chromosome : 1p34.1

Description of this Gene: HECT domain E3 ubiquitin protein ligase 3

Type of Gene: protein-coding

rs7528534 in HECTD3 gene and Leukemia, Myelocytic, Acute PMID 27903959 2017 Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.