Gene: HELLS

Alternate names for this Gene: ICF4|LSH|Nbla10143|PASG|SMARCA6

Gene Summary: This gene encodes a lymphoid-specific helicase. Other helicases function in processes involving DNA strand separation, including replication, repair, recombination, and transcription. This protein is thought to be involved with cellular proliferation and may play a role in leukemogenesis. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene is located in Chromosome: 10

Location in Chromosome : 10q23.33

Description of this Gene: helicase, lymphoid specific

Type of Gene: protein-coding

rs879253733 in HELLS gene and IMMUNODEFICIENCY-CENTROMERIC INSTABILITY-FACIAL ANOMALIES SYNDROME 4 PMID 26216346 2015 Mutations in CDCA7 and HELLS cause immunodeficiency-centromeric instability-facial anomalies syndrome.

rs7078811 in HELLS gene and RDW - Red blood cell distribution width result PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs7078811 in HELLS gene and Red cell distribution width determination PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.