Gene: HHLA2

Alternate names for this Gene: B7-H5|B7-H7|B7H7|B7y

Gene Summary: This gene encodes a protein ligand found on the surface of monocytes. The encoded protein is thought to regulate cell-mediated immunity by binding to a receptor on T lymphocytes and inhibiting the proliferation of these cells. Alternate splicing results in multiple transcript variants.

Gene is located in Chromosome: 3

Location in Chromosome : 3q13.13

Description of this Gene: HERV-H LTR-associating 2

Type of Gene: protein-coding

rs2016469 in HHLA2 gene and Body mass index PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs113421805 in HHLA2 gene and mathematical ability PMID 30038396 2018 Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.