Gene: HIC1

Alternate names for this Gene: ZBTB29|ZNF901|hic-1

Gene Summary: This gene functions as a growth regulatory and tumor repressor gene. Hypermethylation or deletion of the region of this gene have been associated with tumors and the contiguous-gene syndrome, Miller-Dieker syndrome. Alternative splicing of this gene results in multiple transcript variants.

Gene is located in Chromosome: 17

Location in Chromosome : 17p13.3

Description of this Gene: HIC ZBTB transcriptional repressor 1

Type of Gene: protein-coding

rs4480845 in HIC1 gene and Bone Density PMID 29304378 2018 Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects.

rs4455005 in HIC1 gene and Platelet Count measurement PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

rs4480845 in HIC1 gene and Systolic Pressure PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.