Gene: HLA-DPB2
Alternate names for this Gene:
Gene Summary:
Gene is located in Chromosome:
Location in Chromosome :
Description of this Gene:
Type of Gene:
rs3117006 in
HLA-DPB2 gene and
Asthma
PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.
rs3117006 in
HLA-DPB2 gene and
Attention deficit hyperactivity disorder
PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.
rs117232140 in
HLA-DPB2 gene and
Body Height
PMID 31562340 2019 Characterizing rare and low-frequency height-associated variants in the Japanese population.
rs3117027 in
HLA-DPB2 gene and
Cervix carcinoma
PMID 23482656 2013 Three independent loci in the major histocompatibility complex (MHC) region at 6p21.3 were associated with cervical cancer: the first is adjacent to the MHC class I polypeptide-related sequence A gene (MICA) (rs2516448; OR = 1.42, 95% CI = 1.31 to 1.54; P = 1.6×10(-18)); the second is between HLA-DRB1 and HLA-DQA1 (rs9272143; OR = 0.67, 95% CI = 0.62 to 0.72; P = 9.3×10(-24)); and the third is at HLA-DPB2 (rs3117027; OR=1.25, 95% CI = 1.15 to 1.35; P = 4.9×10(-8)).
rs3117039 in
HLA-DPB2 gene and
Hepatitis B
PMID 21750111 2011 A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population.
PMID 19349983 2009 A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians.
rs1883414 in
HLA-DPB2 gene and
IGA Glomerulonephritis
PMID 25305756 2014 Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens.
rs1883414 in
HLA-DPB2 gene and
Kidney Diseases
PMID 21399633 2011 Genome-wide association study identifies susceptibility loci for IgA nephropathy.
rs1883414 in
HLA-DPB2 gene and
Rheumatoid Arthritis
PMID 19503088 2009 REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.
rs3117008 in
HLA-DPB2 gene and
cervical cancer
PMID 23817570 2013 A genome-wide association study identifies two new cervical cancer susceptibility loci at 4q12 and 17q12.
PMID 23482656 2013 Three independent loci in the major histocompatibility complex (MHC) region at 6p21.3 were associated with cervical cancer: the first is adjacent to the MHC class I polypeptide-related sequence A gene (MICA) (rs2516448; OR = 1.42, 95% CI = 1.31 to 1.54; P = 1.6×10(-18)); the second is between HLA-DRB1 and HLA-DQA1 (rs9272143; OR = 0.67, 95% CI = 0.62 to 0.72; P = 9.3×10(-24)); and the third is at HLA-DPB2 (rs3117027; OR=1.25, 95% CI = 1.15 to 1.35; P = 4.9×10(-8)).