Gene: HNF1A
Alternate names for this Gene: HNF-1A|HNF1|HNF4A|IDDM20|LFB1|MODY3|TCF-1|TCF1
Gene Summary: The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene is located in Chromosome: 12
Location in Chromosome : 12q24.31
Description of this Gene: HNF1 homeobox A
Type of Gene: protein-coding
Gene: C12orf43
Alternate names for this Gene: Custos
Gene Summary:
Gene is located in Chromosome: 12
Location in Chromosome : 12q24.31
Description of this Gene: chromosome 12 open reading frame 43
Type of Gene: protein-coding
rs735396 in
HNF1A;C12orf43 gene and
C-reactive protein measurement
PMID 23844046 2013 Are C-reactive protein associated genetic variants associated with serum levels and retinal markers of microvascular pathology in Asian populations from Singapore?
PMID 24763700 2014 New variants including ARG1 polymorphisms associated with C-reactive protein levels identified by genome-wide association and pathway analysis.