Gene: HOXA3

Alternate names for this Gene: HOX1|HOX1E

Gene Summary: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Three transcript variants encoding two different isoforms have been found for this gene.

Gene is located in Chromosome: 7

Location in Chromosome : 7p15.2

Description of this Gene: homeobox A3

Type of Gene: protein-coding

Gene: HOXA-AS3

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Gene: HOXA5

Alternate names for this Gene: HOX1|HOX1.3|HOX1C

Gene Summary: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis.

Gene is located in Chromosome: 7

Location in Chromosome : 7p15.2

Description of this Gene: homeobox A5

Type of Gene: protein-coding