Gene: HOXB5

Alternate names for this Gene: HHO.C10|HOX2|HOX2A|HU-1|Hox2.1

Gene Summary: This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue.

Gene is located in Chromosome: 17

Location in Chromosome : 17q21.32

Description of this Gene: homeobox B5

Type of Gene: protein-coding

Gene: HOXB3

Alternate names for this Gene: HOX2|HOX2G|Hox-2.7

Gene Summary: This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML).

Gene is located in Chromosome: 17

Location in Chromosome : 17q21.32

Description of this Gene: homeobox B3

Type of Gene: protein-coding

Gene: HOXB-AS3

Alternate names for this Gene: -

Gene Summary:

Gene is located in Chromosome: 17

Location in Chromosome : 17q21.32

Description of this Gene: HOXB cluster antisense RNA 3

Type of Gene: ncRNA

rs9299 in HOXB5;HOXB3;HOXB-AS3 gene and Body mass index PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs9299 in HOXB5;HOXB3;HOXB-AS3 gene and Obesity PMID 22484627 2012 A genome-wide association meta-analysis identifies new childhood obesity loci.