Gene: HOXB7

Alternate names for this Gene: HHO.C1|HOX2|HOX2C|Hox-2.3

Gene Summary: This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma.

Gene is located in Chromosome: 17

Location in Chromosome : 17q21.32

Description of this Gene: homeobox B7

Type of Gene: protein-coding

rs890431 in HOXB7 gene and Diastolic blood pressure PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs7406910 in HOXB7 gene and Hypertensive disease PMID 27618447 2016 Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.

rs7406910 in HOXB7 gene and Mean blood pressure PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs7406910 in HOXB7 gene and Systolic Pressure PMID 27618447 2016 Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.