Gene: HOXD1

Alternate names for this Gene: HOX4|HOX4G|Hox-4.7

Gene Summary: This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. This nuclear protein functions as a sequence-specific transcription factor that is involved in differentiation and limb development. Mutations in this gene have been associated with severe developmental defects on the anterior-posterior (a-p) limb axis.

Gene is located in Chromosome: 2

Location in Chromosome : 2q31.1

Description of this Gene: homeobox D1

Type of Gene: protein-coding

Gene: MIR7704

Alternate names for this Gene: hsa-mir-7704

Gene Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Gene is located in Chromosome: 2

Location in Chromosome : 2q31.1

Description of this Gene: microRNA 7704

Type of Gene: ncRNA

Gene: HAGLR

Alternate names for this Gene: HOXD-AS1|MIR7704HG|Mdgt

Gene Summary:

Gene is located in Chromosome: 2

Location in Chromosome : 2q31.1

Description of this Gene: HOXD antisense growth-associated long non-coding RNA

Type of Gene: ncRNA

rs150457564 in HOXD1;MIR7704;HAGLR gene and Glomerular Filtration Rate PMID 31015462 2019 Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis.