Gene: HTR4

Alternate names for this Gene: 5-HT4|5-HT4R

Gene Summary: This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described.

Gene is located in Chromosome: 5

Location in Chromosome : 5q32

Description of this Gene: 5-hydroxytryptamine receptor 4

Type of Gene: protein-coding

rs58862611 in HTR4 gene and Systolic Pressure PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.