Gene: HTRA1

Alternate names for this Gene: ARMD7|CADASIL2|CARASIL|HtrA|L56|ORF480|PRSS11

Gene Summary: This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7.

Gene is located in Chromosome: 10

Location in Chromosome : 10q26.13

Description of this Gene: HtrA serine peptidase 1

Type of Gene: protein-coding

Gene: LOC105378526

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

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rs781563777 in HTRA1;LOC105378526 gene and CEREBRAL ARTERIOPATHY, AUTOSOMAL DOMINANT, WITH SUBCORTICAL INFARCTS AND LEUKOENCEPHALOPATHY, TYPE 2 PMID 26063658 2015 Heterozygous HTRA1 mutations are associated with autosomal dominant cerebral small vessel disease.