Gene: IFNL2

Alternate names for this Gene: IFNL2a|IFNL3a|IL-28A|IL28A

Gene Summary: This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).

Gene is located in Chromosome: 19

Location in Chromosome : 19q13.2

Description of this Gene: interferon lambda 2

Type of Gene: protein-coding

rs664893 in IFNL2 gene and Narcolepsy PMID 19629137 2009 Genome-wide association database developed in the Japanese Integrated Database Project.