Gene: IGF1

Alternate names for this Gene: IGF|IGF-I|IGFI|MGF

Gene Summary: The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein.

Gene is located in Chromosome: 12

Location in Chromosome : 12q23.2

Description of this Gene: insulin like growth factor 1

Type of Gene: protein-coding

Gene: LINC02456

Alternate names for this Gene:

Gene Summary:

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rs972936 in IGF1;LINC02456 gene and Forced expiratory volume function PMID 30804560 2019 New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.

rs5742663 in IGF1;LINC02456 gene and Triglycerides measurement PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

rs972936 in IGF1;LINC02456 gene and Vital capacity PMID 30804560 2019 New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.

rs972936 in IGF1;LINC02456 gene and peak expiratory flow (procedure) PMID 30804560 2019 New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.