Gene: IL17F
Alternate names for this Gene: CANDF6|IL-17F|ML-1|ML1
Gene Summary: The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1.
Gene is located in Chromosome: 6
Location in Chromosome : 6p12.2
Description of this Gene: interleukin 17F
Type of Gene: protein-coding
rs763780 in
IL17F gene and
Pancreatic carcinoma
PMID 22142827 2012 A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303.
PMID 28470677 2017 Genetic polymorphisms associated with pancreatic cancer survival: a genome-wide association study.