Gene: IL17RD

Alternate names for this Gene: HH18|IL-17RD|IL17RLM|SEF

Gene Summary: This gene encodes a membrane protein belonging to the interleukin-17 receptor (IL-17R) protein family. The encoded protein is a component of the interleukin-17 receptor signaling complex, and the interaction between this protein and IL-17R does not require the interleukin. The gene product also affects fibroblast growth factor signaling, inhibiting or stimulating growth through MAPK/ERK signaling. Alternate splicing generates multiple transcript variants encoding distinct isoforms.

Gene is located in Chromosome: 3

Location in Chromosome : 3p14.3

Description of this Gene: interleukin 17 receptor D

Type of Gene: protein-coding

rs200974175 in IL17RD gene and Blood Protein Measurement PMID 29875488 2018 Genomic atlas of the human plasma proteome.

rs6445857 in IL17RD gene and Body Height PMID 31562340 2019 Characterizing rare and low-frequency height-associated variants in the Japanese population.

rs184758350 in IL17RD gene and HYPOGONADOTROPIC HYPOGONADISM 18 WITH OR WITHOUT ANOSMIA PMID 23643382 2013 Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism.

rs6787775 in IL17RD gene and Waist-Hip Ratio PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.