Gene: IL1RL1

Alternate names for this Gene: DER4|FIT-1|IL33R|ST2|ST2L|ST2V|T1

Gene Summary: The protein encoded by this gene is a member of the interleukin 1 receptor family. Studies of the similar gene in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) and interleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. Alternative splicing of this gene results in multiple transcript variants.

Gene is located in Chromosome: 2

Location in Chromosome : 2q12.1

Description of this Gene: interleukin 1 receptor like 1

Type of Gene: protein-coding

rs12470864 in IL1RL1 gene and Adult onset asthma PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs12470864 in IL1RL1 gene and Allergic Reaction PMID 29083406 2017 Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.

rs12470864 in IL1RL1 gene and Asthma PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs12470864 in IL1RL1 gene and Interleukin 1 Receptor-Like 1 Measurement PMID 28240269 2017 Connecting genetic risk to disease end points through the human blood plasma proteome.