Gene: IL27RA

Alternate names for this Gene: CRL1|IL-27RA|IL27R|TCCR|WSX1|zcytor1

Gene Summary: In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein.

Gene is located in Chromosome: 19

Location in Chromosome : 19p13.12

Description of this Gene: interleukin 27 receptor subunit alpha

Type of Gene: protein-coding