Gene: IL36B

Alternate names for this Gene: FIL1|FIL1-(ETA)|FIL1H|FILI-(ETA)|IL-1F8|IL-1H2|IL1-ETA|IL1F8|IL1H2

Gene Summary: The protein encoded by this gene is a member of the interleukin 1 cytokine family. Protein structure modeling indicated that this cytokine may contain a 12-stranded beta-trefoil structure that is conserved between IL1A (IL-A alpha) and IL1B (IL-1 beta). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.

Gene is located in Chromosome: 2

Location in Chromosome : 2q14.1

Description of this Gene: interleukin 36 beta

Type of Gene: protein-coding

rs10496447 in IL36B gene and Interleukin 1 Beta Measurement PMID 30206230 2018 GWAS for Interleukin-1β levels in gingival crevicular fluid identifies IL37 variants in periodontal inflammation.