Gene: INA

Alternate names for this Gene: NEF5|NF-66|TXBP-1

Gene Summary: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene is a member of the intermediate filament family and is involved in the morphogenesis of neurons.

Gene is located in Chromosome: 10

Location in Chromosome : 10q24.33

Description of this Gene: internexin neuronal intermediate filament protein alpha

Type of Gene: protein-coding

rs1163085 in INA gene and Anxiety PMID 29942085 2018 Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.

rs1163087 in INA gene and Glomerular Filtration Rate PMID 31451708 2019 Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program.