Gene: INPP5F

Alternate names for this Gene: MSTP007|MSTPO47|SAC2|hSAC2

Gene Summary: The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase and contains a Sac domain. The activity of this protein is specific for phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene is located in Chromosome: 10

Location in Chromosome : 10q26.11

Description of this Gene: inositol polyphosphate-5-phosphatase F

Type of Gene: protein-coding

rs117896735 in INPP5F gene and Parkinson Disease PMID 28892059 2017 A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci.

PMID 25064009 2014 Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease.