Gene: INSL6

Alternate names for this Gene: RIF1

Gene Summary: The protein encoded by this gene contains a classical signature of the insulin superfamily and is significantly similar to relaxin and relaxin-like factor. This gene is preferentially expressed in testis. Its expression in testis is restricted to interstitial cells surrounding seminiferous tubules, which suggests a role in sperm development and fertilization.

Gene is located in Chromosome: 9

Location in Chromosome : 9p24.1

Description of this Gene: insulin like 6

Type of Gene: protein-coding

rs145699582 in INSL6 gene and Arthritis, Psoriatic PMID 26626624 2015 Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture.

rs143639284 in INSL6 gene and response to bronchodilator PMID 26634245 2015 A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.