Gene: INTS12

Alternate names for this Gene: INT12|PHF22|SBBI22

Gene Summary: INTS12 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008].

Gene is located in Chromosome: 4

Location in Chromosome : 4q24

Description of this Gene: integrator complex subunit 12

Type of Gene: protein-coding

Gene: GSTCD

Alternate names for this Gene:

Gene Summary:

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Description of this Gene:

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rs11727735 in INTS12;GSTCD gene and Chronic Obstructive Airway Disease PMID 28166215 2017 Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis.

rs11722225 in INTS12;GSTCD gene and Forced expiratory volume function PMID 30804560 2019 New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.

rs10050333 in INTS12;GSTCD gene and Pulmonary function PMID 20010835 2010 Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function.

rs10050333 in INTS12;GSTCD gene and Pulmonary function (finding) PMID 20010835 2010 Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function.

rs11722225 in INTS12;GSTCD gene and Vital capacity PMID 30804560 2019 New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.

rs11722225 in INTS12;GSTCD gene and peak expiratory flow (procedure) PMID 30804560 2019 New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.