Gene: IPCEF1

Alternate names for this Gene: PIP3-E

Gene Summary:

Gene is located in Chromosome: 6

Location in Chromosome : 6q25.2

Description of this Gene: interaction protein for cytohesin exchange factors 1

Type of Gene: protein-coding

Gene: OPRM1

Alternate names for this Gene: LMOR|M-OR-1|MOP|MOR|MOR1|OPRM

Gene Summary: This gene encodes one of at least three opioid receptors in humans; the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. The MOR also has an important role in dependence to other drugs of abuse, such as nicotine, cocaine, and alcohol via its modulation of the dopamine system. The NM_001008503.2:c.118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene. Though the canonical MOR belongs to the superfamily of 7-transmembrane-spanning G-protein-coupled receptors some isoforms of this gene have only 6 transmembrane domains.

Gene is located in Chromosome: 6

Location in Chromosome : 6q25.2

Description of this Gene: opioid receptor mu 1

Type of Gene: protein-coding

rs2236256 in IPCEF1;OPRM1 gene and Chronic Lymphocytic Leukemia PMID 24292274 2014 A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.

rs2236256 in IPCEF1;OPRM1 gene and Small Lymphocytic Lymphoma PMID 24292274 2014 A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.