Gene: IPO11

Alternate names for this Gene: RanBP11

Gene Summary: Importins, including IPO11, are a members of the karyopherin/importin-beta family of transport receptors (see KPNB1; 602738) that mediate nucleocytoplasmic transport of protein and RNA cargoes (Plafker and Macara, 2000 [PubMed 11032817]).[supplied by OMIM, Sep 2008].

Gene is located in Chromosome: 5

Location in Chromosome : 5q12.1

Description of this Gene: importin 11

Type of Gene: protein-coding

Gene: KIF2A

Alternate names for this Gene: CDCBM3|HK2|KIF2

Gene Summary: The protein encoded by this gene is a plus end-directed motor required for normal mitotic progression. The encoded protein is required for normal spindle activity during mitosis and is necessary for normal brain development. Several transcript variants encoding different isoforms have been found for this gene.

Gene is located in Chromosome: 5

Location in Chromosome : 5q12.1

Description of this Gene: kinesin family member 2A

Type of Gene: protein-coding

rs1301064 in IPO11;KIF2A gene and Leukemia, Myelocytic, Acute PMID 27903959 2017 Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.