Gene: IRF2BP2

Alternate names for this Gene: CVID14

Gene Summary: This gene encodes an interferon regulatory factor-2 (IRF2) binding protein that interacts with the C-terminal transcriptional repression domain of IRF2. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene is located in Chromosome: 1

Location in Chromosome : 1q42.3

Description of this Gene: interferon regulatory factor 2 binding protein 2

Type of Gene: protein-coding

rs1553319504 in IRF2BP2 gene and IMMUNODEFICIENCY, COMMON VARIABLE, 14 PMID 27016798 2016 Mutation in IRF2BP2 is responsible for a familial form of common variable immunodeficiency disorder.

rs8823 in IRF2BP2 gene and mathematical ability PMID 30038396 2018 Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.