Gene: IRGM
Alternate names for this Gene: IFI1|IRGM1|LRG-47|LRG47
Gene Summary: This gene encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene is located in Chromosome: 5
Location in Chromosome : 5q33.1
Description of this Gene: immunity related GTPase M
Type of Gene: protein-coding