Gene: ITPR3

Alternate names for this Gene: IP3R|IP3R3

Gene Summary: This gene encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth.

Gene is located in Chromosome: 6

Location in Chromosome : 6p21.31

Description of this Gene: inositol 1,4,5-trisphosphate receptor type 3

Type of Gene: protein-coding

Gene: LOC105375023

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Gene: LOC101929188

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rs71565398 in ITPR3;LOC105375023;LOC101929188 gene and Asthma PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs71565398 in ITPR3;LOC105375023;LOC101929188 gene and Attention deficit hyperactivity disorder PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.