Gene: ITPRID1

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

Type of Gene:

Gene: PDE1C

Alternate names for this Gene: DFNA74|Hcam3|cam-PDE 1C|hCam-3

Gene Summary: This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta.

Gene is located in Chromosome: 7

Location in Chromosome : 7p14.3

Description of this Gene: phosphodiesterase 1C

Type of Gene: protein-coding

rs4141001 in ITPRID1;PDE1C gene and Psoriasis PMID 25854761 2015 Whole-exome SNP array identifies 15 new susceptibility loci for psoriasis.