Gene: JMJD7-PLA2G4B

Alternate names for this Gene: HsT16992|cPLA2-beta

Gene Summary: This locus represents naturally-occurring readthrough transcription between the neighboring jumonji domain containing 7 (JMJD7) and phospholipase A2, group IVB (cytosolic) (PLA2G4B) genes. Readthrough transcripts encode fusion proteins that share amino acid sequence with each individual gene product, including a partial JmjC domain and downstream C2 and phospholipase A2 domains. Alternatively spliced transcript variants have been observed.

Gene is located in Chromosome: 15

Location in Chromosome : 15q15.1

Description of this Gene: JMJD7-PLA2G4B readthrough

Type of Gene: protein-coding

Gene: JMJD7

Alternate names for this Gene: -

Gene Summary: This gene encodes a highly conserved protein with a JmjC domain, which are part of the cupin metalloenzyme superfamily. JmjC proteins may function as 2-oxoglutarate-Fe(II)-dependent dioxygenases. Most tissues also express read-through transcripts from this gene into the downstream phospholipase A2, group IVB (cytosolic) gene, some of which may encode fusion proteins combining the N-terminus of this protein with the phospholipase A2, group IVB protein.

Gene is located in Chromosome: 15

Location in Chromosome : 15q15.1

Description of this Gene: jumonji domain containing 7

Type of Gene: protein-coding

rs1531140 in JMJD7-PLA2G4B;JMJD7 gene and Triglycerides measurement PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.