Gene: KAT2A

Alternate names for this Gene: GCN5|GCN5L2|PCAF-b|hGCN5

Gene Summary: KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).[supplied by OMIM, Sep 2009]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC039907.1, BC032743.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000225916.10/ ENSP00000225916.5 RefSeq Select criteria :: based on conservation ##RefSeq-Attributes-END##

Gene is located in Chromosome: 17

Location in Chromosome : 17q21.2

Description of this Gene: lysine acetyltransferase 2A

Type of Gene: protein-coding