Gene: KAT7

Alternate names for this Gene: HBO1|HBOA|MYST2|ZC2HC7

Gene Summary: The protein encoded by this gene is part of the multimeric HBO1 complex, which possesses histone H4-specific acetyltransferase activity. This activity is required for functional replication origins and is involved in transcriptional activation of some genes. In both cases, the acetylation of histone H4 helps unfold chromatin so that the DNA can be accessed and replicated or transcribed.

Gene is located in Chromosome: 17

Location in Chromosome : 17q21.33

Description of this Gene: lysine acetyltransferase 7

Type of Gene: protein-coding

rs572017140 in KAT7 gene and Finding of Mean Corpuscular Hemoglobin PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

rs572017140 in KAT7 gene and Mean Corpuscular Volume (result) PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.