Gene: KCNG4

Alternate names for this Gene: KV6.3|KV6.4

Gene Summary: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member functions as a modulatory subunit. The gene has strong expression in brain. Multiple alternatively spliced variants have been found in normal and cancerous tissues.

Gene is located in Chromosome: 16

Location in Chromosome : 16q24.1

Description of this Gene: potassium voltage-gated channel modifier subfamily G member 4

Type of Gene: protein-coding

rs145986148 in KCNG4 gene and Chronic Obstructive Airway Disease PMID 26503814 2016 A genome-wide analysis of the response to inhaled β2-agonists in chronic obstructive pulmonary disease.