Gene: KCNH8

Alternate names for this Gene: ELK|ELK1|Kv12.1|elk3

Gene Summary: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit.

Gene is located in Chromosome: 3

Location in Chromosome : 3p24.3

Description of this Gene: potassium voltage-gated channel subfamily H member 8

Type of Gene: protein-coding

rs727139 in KCNH8 gene and Chronic venous insufficiency PMID 28374850 2017 Genome-wide association analysis for chronic venous disease identifies EFEMP1 and KCNH8 as susceptibility loci.