Gene: KCNMA1

Alternate names for this Gene: BKTM|CADEDS|IEG16|KCa1.1|LIWAS|MaxiK|PNKD3|SAKCA|SLO|SLO-ALPHA|SLO1|bA205K10.1|hSlo|mSLO1

Gene Summary: MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene is located in Chromosome: 10

Location in Chromosome : 10q22.3

Description of this Gene: potassium calcium-activated channel subfamily M alpha 1

Type of Gene: protein-coding

Gene: KCNMA1-AS1

Alternate names for this Gene: -

Gene Summary:

Gene is located in Chromosome: 10

Location in Chromosome : 10q22.3

Description of this Gene: KCNMA1 antisense RNA 1

Type of Gene: ncRNA

rs10762738 in KCNMA1;KCNMA1-AS1 gene and Hypospadias PMID 25108383 2014 Genome-wide association analyses identify variants in developmental genes associated with hypospadias.

rs2116830 in KCNMA1;KCNMA1-AS1 gene and Obesity PMID 21708048 2011 Genome wide association study identifies KCNMA1 contributing to human obesity.